Brain trauma affects millions – here are some of their stories

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Brain trauma affects millions – here are some of their stories

TBI Action Alliance is accelerating and advancing Traumatic Brain Injury research and awareness.

The TBI Action Alliance (TBIAA), founded by Cohen Veterans Bioscience, is the first-ever large-scale coordinated effort to accelerate Traumatic Brain Injury (TBI) research and awareness.

Twenty-two organizations have come together as part of the Alliance to bring awareness to TBI and to advance diagnostics and therapeutics that can help address this widespread and significantly under-addressed condition.

The TBI Action Alliance will deliver improved brain health and outcomes for individuals who have experienced traumatic brain injuries through collective expertise and multi-sector action to deliver innovative solutions.  

TBI Action Alliance
TBI Action Alliance

We’re the only organization that brings together stakeholders across the ecosystem to speed development of new therapeutics and diagnostics and enhance awareness of TBI as a public health crisis. Our work is urgent, because even though every American is at risk for a TBI, there are not enough diagnostics or treatments available to help. In fact, there’s been almost no innovation in this area at all.

Our team of partners has pioneered the only collaboration based, patient centric approach that radically accelerates research and development focused on diagnosing and treating traumatic brain injuries.

But we’re about far more than just understanding and planning. We’re identifying and prioritizing the most promising solutions and approaches, and we’re relentless about doing what it takes to bring them forward and make real progress.

How the TBI Action Alliance is making an impact

Raise Awareness and Advocate for TBI Research

Raise Awareness & Advocate

We present a unified and powerful voice to policy makers, funders, scientists and others who support TBI research efforts. We work to ensure our priorities become theirs.

TBI Action Alliance - Innovation in TBI Research

Spark a New Era of Innovation

We bring together capital and aligned research priorities to attract innovative thinkers and foster the advancement of new innovative approaches for TBI.

Establish a TBI National Research Agenda

Establish a National Research Agenda

We are advancing a TBI Precision Research Roadmap to support scientific, regulatory and government policies that place TBI research at the top of the national agenda and ensure adequate funding and resources to execute it.

Put Patients at the Center of Research Endeavors

Put Patients at the Center

We are engaging the community in establishing the Research Roadmap and ensuring it is executed.

Chart Progress

Chart Progress

We track progress against roadmap milestones and report out to the Alliance membership progress of collective efforts.

We’re connecting leading experts and catalyzing collaborative action

The TBI Precision Research Roadmap focuses on 7 lines of effort:

  • 1
    Injury burden: Identify the burden of disease across all populations and injury severities as determined by incidence, prevalence and long-term trajectories of patients suffering from TBI.
  • 2
    Disease models: Develop an array of translationally valid disease models (preclinical and computational) based on biological understanding of trauma pathogenesis and disease phenotypes that support evaluation of novel therapies.
  • 3
    Precision diagnosis: Identify, develop and validate diagnostic, prognostic and predictive biomarkers for TBI to develop first-generation diagnostic tests.
  • 4
    Targeted therapeutics: Validate therapeutic targets & fast track a first-generation of TBI (wellness, device, digital, drug) therapeutics targeted to the right person at the right time.
  • 5
    Clinical practice implementation: Accelerate adoption of best practices, clinical practice guidelines, and precision therapeutic approaches to optimize brain health outcomes.
  • 6
    Translational infrastructure and enabling technologies: Identify and address infrastructure, incentives, regulatory and technology gaps to advance the TBI roadmap.
  • 7
    Awareness and advocacy: Place TBI at the top of the U.S. Public Policy agenda and raise awareness to reduce stigma of brain injury, encourage treatment-seeking, and enable access and reimbursement of care.
How the TBI Action Alliance Works

"At the TBI Action Alliance, our belief is that success can be achieved through a collaborative model. We aim to identify research gaps, work collectively, and ensure a coordinated effort towards making an impact in the lives of those affected by traumatic brain injuries.”

Join the alliance and become a partner

Brain Trauma Blueprint Process

The Roadmap

Cohen Veterans Bioscience (CVB) established the Brain Trauma Blueprint – a framework for generating and executing precision research roadmaps.

Through this framework, CVB has convened TBI Researchers and other stakeholders at State of the Science Summits to identify and publish consensus challenges and recommendations for TBI research.

Brain trauma affects millions – here are some of their stories

Join the TBI Action Alliance

We are at a crossroads of TBI Research. While there has been increased awareness and funding, we have not made enough progress.

The time is now to embark on a new model of research, where researchers, the government, industry and those with lived experiences come together to focus on achieving specific and measurable objectives that will transform the lives of people who suffer a TBI.

We ask that you join us in this critical fight for our Veterans and others who have suffered long enough and become a Member of the TBI Action Alliance.

Brain trauma affects millions – here are some of their stories

Get the facts about Traumatic Brain Injury (TBI)

TBI is change in brain function or brain pathology caused by an external force that can occur in traffic, at home, at work, at play, during sports activities, and on the battlefield.1

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70 Million

Individuals worldwide suffer a traumatic brain injury (TBI) each year.2


Military service members were affected by TBIs between 2000-2015 – it’s the most common traumatic injury in the U.S. military.3


The number of emergency department visits that happen each year from TBIs in adults over 65 due to falls.4


Children (0-14 years old) suffer a TBI each year due to falls and sports related accidents.5

5.3 Million

Americans are living with a long-term disability due to a TBI.

$50 Billion

In 2015, the cost for direct TBI medical care in the U.S. was estimated at more than $50 Billion per year.6

~$203 Million

The annual investment by the NIH in TBI-related research programs, representing less than half a percent of NIH’s $45 Billion budget.7


Times more likely someone with a history of TBI or PTSD will attempt suicide compared to those without the diagnosis.8

5.3 Million

The number of Americans with traumatic brain injuries that we can help each year with your contributions.

Sources / Citations

1 Manley, G.T. and Maas, A.I. (2013) JAMA 310, 473-474.

2 Haarbauer-Krupa J, et al. (2021) Epidemiology of chronic effects of traumatic brain injury. Journal of neurotrauma. 2021 Dec 1;38(23):3235-47.

3 Helmick et al (2015) Brain Imaging and Behavior. Sep;9(3):358-66.

4 Gardner et al. (2015) Journal of Neurotrauma, 35:889–906. doi: 10.1089/neu.2017.5371.

5 et al. (2016) World Neurosurgery, 91:497-509.e1 doi: 10.1016/j.wneu.2016.03.045.

6 Frieden TR, Houry D, Baldwiin G. (2015) Report to Congress on Traumatic Brain Injury in the United States: Epidemiology and Rehabilitation. Atlanta, GA: CDC 2015.

7 (2022).


Brain trauma affects millions – here are some of their stories

TBI Action Alliance Members, Partners and Sponsors

The TBI Action Alliance welcomes more than 40 new academic and private sector scientists, funding organizations, advocates and policymakers. Each has a strong commitment to advocating for and accelerating traumatic brain injury research and awareness. Together, they aim to bring forward research initiatives and policy agendas outlined in a collaborative roadmap designed to accelerate the development of the first generation of precision diagnostics and targeted treatments for brain trauma. The roadmap will also address systemic changes required to ensure all those suffering from trauma-related brain injuries can get access to these new innovations, as well as other support and care.


Platinum Sponsor

Gold Sponsor

Silver Sponsor

Silver Sponsor

Silver Sponsor

Event Sponsors

Member Benefits & Information

Thank you for contacting us to learn more about sponsoring the TBI Action Alliance.

A member of our team will contact you soon to discuss sponsorship opportunities and more.

Thanks for joining the TBI Action Alliance as a member.

You will receive a confirmation email soon; please contact us if you have any questions.

Institutional Sponsorship Program & Benefits Summary

The Sponsorship Program provides non-government funding to support the projects outlined in the TBI Precision Research Roadmap to accelerate progress and results.

Your sponsorship will help us drive a new era of research for TBI that advances a first generation of FDA-approved diagnostics and treatments.

Sponsorship levels are based on total annual or combined (3 year) commitment for individual or multiple programs, projects or infrastructure efforts delineated by the Precision TBI Research Roadmap. Commitments are formalized through a Grant or Gift Agreement with Cohen Veterans Bioscience, subject to Alliance terms & conditions, and payments are made annually in accordance with commitment terms.

Please contact us with any questions or to learn more about sponsorship.

Sponsorship Level & Benefits

Inaugural Sponsor




Industry/Not-for-profit/Foundations/Individual Donors

Gold or Platinum Level committed by March 31, 2023




Seat on Inaugural Executive Committee (Y1)


Weighted vote on Industry, Foundation or Partners Stakeholder Council

After Y1, to level of sponsorship




Invitations to attend BTB Summit Annual Conferences





Branding opportunities

Premium placement & recognition of support

Premium placement & recognition of support

Logo on Program Materials

Logo on Program Materials

Membership Program benefits*





  *Refer to Membership Program for details

Contact Us to Learn More

Join the TBI Action Alliance as an Institution

Member Benefits & Information